Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262605 | 0.78 | ALDH1A1 (0.51) | TP53MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8580093 | 0.76 | CA12 (0.49) | HPGDTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7817781 | 0.75 | CA12 (0.37) | HPGDMEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL9255027 | 0.74 | CA12 (0.45) | HPGDTP53MEN1KMT2AEGFR | |
| SCHEMBL9262412 | 0.74 | NAAA (0.47) | HPGDTSHRSMN1; SMN2EGFRALDH1A1 | |
| SCHEMBL9258029 | 0.72 | DRD3 (0.37) | TSHRKDM4EDRD3OPRM1OPRD1 | |
| SCHEMBL9251348 | 0.70 | CA12 (0.49) | HPGDMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL9255807 | 0.69 | MAPT (0.41) | TP53SMN1; SMN2NPSR1ALDH1A1LMNA | |
| SCHEMBL9260062 | 0.68 | CA12 (0.37) | HPGDMEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL9189058 | 0.67 | TP53 (0.58) | HPGDTP53MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |