Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257253 | 0.90 | KMT2A (0.48) | KMT2AMEN1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL9255965 | 0.90 | CYP1A2 (0.44) | — | |
| SCHEMBL9255967 | 0.90 | CYP1A2 (0.44) | — | |
| SCHEMBL9258643 | 0.82 | KMT2A (0.50) | KMT2AMEN1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL9260633 | 0.78 | ALDH1A1 (0.45) | KMT2AMEN1DPP7 | |
| SCHEMBL9257263 | 0.78 | KMT2A (0.46) | KMT2AMEN1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL13003260 | 0.78 | SIGMAR1 (0.68) | KMT2AMEN1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL9262360 | 0.74 | CYP1A2 (0.41) | POLB | |
| SCHEMBL5402061 | 0.73 | SIGMAR1 (0.68) | KMT2ASIGMAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL10799864 | 0.73 | SIGMAR1 (0.61) | KMT2ASIGMAR1DRD4POLBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |