Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257263 | 0.89 | KMT2A (0.46) | KMT2AMEN1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL9257535 | 0.88 | MAPT (0.46) | KMT2A | |
| SCHEMBL9258638 | 0.82 | KMT2A (0.52) | KMT2AMEN1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL9257253 | 0.79 | KMT2A (0.48) | KMT2AMEN1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL13003260 | 0.76 | SIGMAR1 (0.68) | KMT2AMEN1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL5402061 | 0.72 | SIGMAR1 (0.68) | KMT2ASIGMAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL9256395 | 0.71 | MAPT (0.47) | L3MBTL1POLB | |
| SCHEMBL7268908 | 0.70 | SIGMAR1 (0.79) | SIGMAR1L3MBTL1POLB | |
| SCHEMBL9261597 | 0.70 | GABBR2 (0.51) | KMT2AMEN1L3MBTL1POLBDRD3 | |
| SCHEMBL3164487 | 0.70 | SIGMAR1 (0.74) | KMT2AMEN1SIGMAR1POLBDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |