Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477670 | 0.86 | ALDH1A1 (0.49) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL73144 | 0.82 | ALDH1A1 (0.54) | ALDH1A1PKMGAASLC1A2HDAC3 | |
| SCHEMBL44725 | 0.81 | ALDH1A1 (0.50) | ALDH1A1PKMSLC1A2HDAC1HDAC2 | |
| SCHEMBL2128258 | 0.76 | ALDH1A1 (0.49) | ALDH1A1PKMSLC1A2KMT2AKDM4E | |
| SCHEMBL2304471 | 0.76 | ALDH1A1 (1.00) | ALDH1A1PKMGAASLC1A2HDAC3 | |
| SCHEMBL1563867 | 0.76 | ALDH1A1 (1.00) | ALDH1A1PKMGAASLC1A2HDAC3 | |
| SCHEMBL9398017 | 0.74 | ALDH1A1 (0.48) | ALDH1A1PKMKMT2AKDM4EMAPT | |
| SCHEMBL616908 | 0.73 | ALDH1A1 (0.54) | ALDH1A1PKMPOLBKMT2AHSD17B10 | |
| SCHEMBL6386661 | 0.72 | ALDH1A1 (0.90) | ALDH1A1PKMGAAHDAC3HDAC4 | |
| SCHEMBL14433740 | 0.70 | ALDH1A1 (0.66) | ALDH1A1PKMGAAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395924-A | Oligosaccharide or glycopeptide bound to lectin and conjugated with cell binding agent, improved targeting of cells for cytolysis | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1995-03-07 | — | — | US | disclosed |
| US-5239062-A | Blocked lectins, methods and affinity support for making same using affinity ligands, and method of killing selected cell populations having reduced nonselective cytotoxicity | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1993-08-24 | — | — | US | disclosed |