Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477670 | 0.88 | ALDH1A1 (0.49) | ALDH1A1PKMTSHRKDM4ENPC1 | |
| SCHEMBL616908 | 0.76 | ALDH1A1 (0.54) | ALDH1A1PKMTSHRNPC1SMN1; SMN2 | |
| SCHEMBL9398036 | 0.74 | ITGB3 (0.40) | ALDH1A1KMT2A | |
| SCHEMBL9258688 | 0.74 | ALDH1A1 (0.61) | ALDH1A1PKMTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL2011394 | 0.72 | ITGB3 (0.36) | ALDH1A1PKMKDM4EKMT2AL3MBTL1 | |
| Acetic Acid SCHEMBL28022541 | 0.71 | MTNR1A (0.45) | ALDH1A1NPC1SMN1; SMN2RAB9ATBXAS1 | |
| SCHEMBL73144 | 0.70 | ALDH1A1 (0.54) | ALDH1A1PKMKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL4826685 | 0.70 | CYP11B1 (0.45) | ALDH1A1PKMSMN1; SMN2CYP11B1TBXAS1 | |
| SCHEMBL44725 | 0.68 | ALDH1A1 (0.50) | ALDH1A1PKMNPC1SMN1; SMN2RAB9A | |
| SCHEMBL9398031 | 0.68 | SMN1; SMN2 (0.42) | ALDH1A1PKMTSHRNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329794-B1 | METHOD FOR ASSAYING HUMAN LUNG SURFACE ACTIVE SUBSTANCE | TEIJIN LTD (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0329794-A1 | METHOD FOR ASSAYING HUMAN LUNG SURFACE ACTIVE SUBSTANCE | TEIJIN LIMITED (JP) | 1989-08-30 | — | — | EP | disclosed |