Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258703 | 1.00 | RIPK1 (0.44) | RIPK1LMNACYP2C19HSD17B10ATM | |
| SCHEMBL8544519 | 0.85 | RIPK1 (0.40) | RIPK1LMNACYP2C19HSD17B10 | |
| SCHEMBL8544522 | 0.85 | RIPK1 (0.40) | RIPK1LMNACYP2C19HSD17B10 | |
| SCHEMBL19075666 | 0.83 | LMNA (0.53) | RIPK1LMNACYP2C19HSD17B10ACE | |
| SCHEMBL19075564 | 0.82 | ATM (0.46) | RIPK1LMNACYP2C19HSD17B10ATM | |
| SCHEMBL19075572 | 0.82 | ATM (0.46) | RIPK1LMNACYP2C19HSD17B10ATM | |
| SCHEMBL8539717 | 0.82 | ATM (0.44) | LMNACYP2C19HSD17B10ATMACE | |
| SCHEMBL8539711 | 0.82 | ATM (0.44) | LMNACYP2C19HSD17B10ATMACE | |
| SCHEMBL18701586 | 0.80 | RIPK1 (0.44) | RIPK1LMNAPRMT5WDR77 | |
| SCHEMBL14211002 | 0.79 | HSD17B10 (0.50) | LMNAHSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453430-A | Anticoagulants | SYNTHELABO (FR) | 1995-09-26 | — | — | US | disclosed |