Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453667 | 0.83 | TDP1 (0.59) | FFAR1KEAP1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL8547145 | 0.82 | LDHA (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL27582146 | 0.80 | HDAC1 (0.55) | TDP1RAB9ASMN1; SMN2NPC1HDAC1 | |
| SCHEMBL628245 | 0.79 | CES2 (0.54) | SMN1; SMN2ALDH1A1HDAC8HDAC6MAPK1 | |
| SCHEMBL28297445 | 0.79 | ALDH1A1 (0.54) | TDP1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6380084 | 0.77 | TDP1 (0.55) | FFAR1KEAP1TDP1RAB9ASMN1; SMN2 | |
| Malonic Acid SCHEMBL10486475 | 0.75 | FFAR1 (0.67) | FFAR1KEAP1TDP1SMN1; SMN2HDAC1 | |
| Butane SCHEMBL9116731 | 0.74 | MEN1 (0.32) | GAAHDAC1ALDH1A1HDAC2HDAC8 | |
| SCHEMBL20591033 | 0.72 | BCHE (0.54) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28145122 | 0.72 | ALDH1A1 (0.54) | TDP1RAB9ANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428165-A | Process for making 5-introbarbituric acid and salts thereof | THIOKOL CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |