Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12388585 | 0.83 | KIF11 (0.53) | NOTUMNPC1RAB9AHPGDSHTT | |
| SCHEMBL3964365 | 0.82 | HPGDS (0.58) | NOTUMHPGDSBRD4LTA4H | |
| SCHEMBL14310734 | 0.80 | HPGDS (0.43) | NOTUMNPC1RAB9AHPGDSBRD4 | |
| SCHEMBL15675358 | 0.79 | KIF11 (0.50) | NOTUMNPC1HPGDSKDM4ELTA4H | |
| SCHEMBL16159319 | 0.78 | HPGDS (0.55) | NOTUMHPGDSBRD4LTA4H | |
| SCHEMBL2107190 | 0.77 | S1PR1 (0.38) | NOTUMHPGDSLTA4H | |
| SCHEMBL2152660 | 0.75 | HPGDS (0.61) | HPGDSLTA4H | |
| SCHEMBL3164807 | 0.74 | TGFBR1 (0.54) | NOTUMNPC1RAB9AKMOSCN2A | |
| SCHEMBL764967 | 0.74 | HPGDS (0.50) | HPGDSLTA4H | |
| SCHEMBL5201307 | 0.74 | HPGDS (0.50) | HPGDSBRD4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1241188-A | Heterocyclylmethyl-substed pyrazol derivs. | BAYER AG (DE) | 2000-01-12 | — | — | CN | disclosed |
| US-5476758-A | Film thickness; spectral sensitizer | FUJI PHOTO FILM CO., LTD. (JP) | 1995-12-19 | — | — | US | disclosed |