Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410326 | 0.89 | — | — | |
| SCHEMBL1409720 | 0.82 | ACE2 (0.45) | ACE2FDPSOPRM1 | |
| SCHEMBL2504628 | 0.81 | DNM1 (0.43) | ACE2TSHRSMN1; SMN2FDPSDNM1 | |
| SCHEMBL10938434 | 0.80 | ACE2 (0.48) | ACE2FDPSOPRM1 | |
| SCHEMBL8079439 | 0.80 | ACE2 (0.48) | ACE2FDPSOPRM1 | |
| SCHEMBL448296 | 0.80 | ACE2 (0.48) | ACE2FDPSOPRM1 | |
| SCHEMBL14336195 | 0.80 | ACE2 (0.48) | ACE2FDPSOPRM1 | |
| SCHEMBL4279140 | 0.76 | TSHR (0.46) | ACE2TSHRSMN1; SMN2FDPSDNM1 | |
| SCHEMBL4277175 | 0.76 | OPRM1 (0.50) | ACE2TSHRFDPSDNM1CA2 | |
| SCHEMBL3086101 | 0.75 | ACE2 (0.38) | ACE2TSHRSMN1; SMN2FDPSDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | claimed |
| US-5391564-A | E.g., rhizoxin-13-yl 3-methylthiopropionate; anticarcinogenic agents | SANKYO COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |