SCHEMBL448296

SCHEMBL448296

CCCCCCC(C)C[C]=O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.48
GPR84 Q9NQS5 7/20 0.43
FFAR1 O14842 2/20 0.43
SPHK1 Q9NYA1 1/20 0.43
MAPT P10636 1/20 0.42
OPRM1 P35372 1/20 0.41
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH4 P08319 1/20 0.41
ADH7 P40394 1/20 0.41
FFAR4 Q5NUL3 1/20 0.39
FDPS P14324 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14336195 1.00 ACE2 (0.48) ACE2GPR84FFAR1SPHK1MAPT
SCHEMBL10938434 1.00 ACE2 (0.48) ACE2GPR84FFAR1SPHK1MAPT
SCHEMBL8079439 1.00 ACE2 (0.48) ACE2GPR84FFAR1SPHK1MAPT
SCHEMBL1409720 0.98 ACE2 (0.45) ACE2GPR84FFAR1SPHK1MAPT
SCHEMBL1410326 0.91
SCHEMBL7298035 0.82 FFAR1 (0.40) FFAR1FFAR4
SCHEMBL7298037 0.82 FFAR1 (0.40) FFAR1FFAR4
SCHEMBL269374 0.80
SCHEMBL9258970 0.80 ACE2 (0.34) ACE2OPRM1FDPS
SCHEMBL23925000 0.80 ACE2 (0.52) ACE2GPR84FFAR1SPHK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 463 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3109254-B1 CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE UNIV OSAKA (JP) 2018-04-11 EP claimed
WO-2016079757-A2 NOVEL PROCESSES FOR PREPARING 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES SYMED LABS LIMITED (IN) 2016-05-26 WO claimed
WO-2014045292-A1 IMPROVED PROCESS FOR THE PREPARATION OF LINEZOLID INTERMEDIATE SYMED LABS LIMITED (IN) 2014-03-27 WO claimed
WO-2024135721-A1 METHOD FOR PRODUCING PRODUCTION INTERMEDIATE, PRODUCTION INTERMEDIATE THEREOF, AND METHOD FOR PRODUCING CROSSLINKED ARTIFICIAL NUCLEIC ACID INTERMEDIATE BY USING SAME 田辺三菱製薬株式会社 2024-06-27 WO disclosed
WO-2024101446-A1 MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME ルクサナバイオテク株式会社 2024-05-16 WO disclosed
CN-112513062-B Oligonucleotide-containing small cell lung cancer therapeutic agent 国立大学法人大阪大学 2024-05-10 CN disclosed
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING OSAKA UNIVERSITY (JP) 2024-05-09 US disclosed
CN-117964673-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
CN-117964674-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
US-11939421-B2 Or relating to curing agents HEXCEL COMPOSITES LIMITED (GB) 2024-03-26 US disclosed
US-11879052-B2 Curatives HEXCEL COMPOSITES LIMITED (GB) 2024-01-23 US disclosed
US-5925664-A VISION DEFECTS SANKYO COMPANY, LIMITED (JP) 1999-07-20 US disclosed
EP-0844000-A1 Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis SANKYO COMPANY LIMITED (JP) 1998-05-27 EP disclosed
EP-0795326-A1 OCULAR TENSION DEPRESSANT SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed
CN-1157286-A N,N-dimethyl-1-t-butoxycarbonyl-4-phenylpiperidine-4-carboxamide SANKYO CO (JP) 1997-08-20 CN disclosed
EP-0776893-A1 Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 SANKYO COMPANY LIMITED (JP) 1997-06-04 EP disclosed
US-5556864-A TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS SANKYO COMPANY, LIMITED (JP) 1996-09-17 US disclosed
CN-1102640-A Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory and psychiatric disorders SANKYO CO (JP) 1995-05-17 CN disclosed
EP-0600717-A1 Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis SANKYO COMPANY LIMITED (JP) 1994-06-08 EP disclosed
US-4460445-A PROPYLENE POLYMERS MILLIKEN RESEARCH CORPORATION (US) 1984-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING UPF1, RBM17, NSUN2 ACE2 4291/4885GPR84 2779/4885FFAR1 2468/4885
US-11939421-B2 Or relating to curing agents FABP4, RARA, ADIPOR1 ACE2 1481/4885GPR84 1778/4885FFAR1 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.