Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 18/20 | 0.37 |
| ▸ | LOX | P28300 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263746 | 0.82 | LOXL2 (0.36) | LOXL2LOXCA2 | |
| SCHEMBL9257485 | 0.78 | CA2 (0.45) | LOXL2LOXCA2 | |
| SCHEMBL9259754 | 0.77 | CA2 (0.46) | LOXL2LOXCA2 | |
| SCHEMBL9095364 | 0.75 | LOXL2 (0.48) | LOXL2LOXCA2 | |
| SCHEMBL9095386 | 0.73 | LOXL2 (0.44) | LOXL2LOXCA2KCNH2AOC3 | |
| SCHEMBL7529843 | 0.73 | LOXL2 (0.41) | LOXL2LOXKCNH2AOC3 | |
| SCHEMBL9260481 | 0.72 | LOXL2 (0.37) | LOXL2LOX | |
| SCHEMBL27863764 | 0.71 | LOXL2 (0.66) | LOXL2LOXKCNH2AOC3 | |
| SCHEMBL9095254 | 0.71 | CA2 (0.36) | CA2 | |
| SCHEMBL21963284 | 0.70 | LOXL2 (0.51) | LOXL2LOXKCNH2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029904-A1 | SUBSTITUTED THIAZOLE SULFONAMIDES AS ANTIGLAUCOMA AGENTS | ALLERGAN (US) | 1995-11-09 | — | — | WO | disclosed |