Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 13/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259186 | 0.77 | LOXL2 (0.37) | CA2LOXL2LOX | |
| SCHEMBL9097361 | 0.74 | CA2 (0.51) | CA2 | |
| SCHEMBL9263746 | 0.72 | LOXL2 (0.36) | CA2LOXL2LOX | |
| SCHEMBL9257485 | 0.70 | CA2 (0.45) | CA2LOXL2LOX | |
| SCHEMBL9095364 | 0.70 | LOXL2 (0.48) | CA2LOXL2LOX | |
| SCHEMBL22014645 | 0.70 | CA2 (0.46) | CA2LOXL2 | |
| SCHEMBL9095386 | 0.66 | LOXL2 (0.44) | CA2LOXL2LOX | |
| SCHEMBL22013633 | 0.66 | CA2 (0.36) | CA2LOXL2LOX | |
| SCHEMBL22020358 | 0.66 | CA2 (0.36) | CA2LOXL2LOX | |
| SCHEMBL21963284 | 0.66 | LOXL2 (0.51) | LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029904-A1 | SUBSTITUTED THIAZOLE SULFONAMIDES AS ANTIGLAUCOMA AGENTS | ALLERGAN (US) | 1995-11-09 | — | — | WO | disclosed |