Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 8/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097578 | 0.80 | MAP2K1 (0.37) | MAP2K1MAP2K2KDM4EALDH1A1GLA | |
| SCHEMBL8942453 | 0.73 | EPHA2 (0.35) | KDM4EALDH1A1HPGD | |
| SCHEMBL9097147 | 0.73 | ALDH1A1 (0.42) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL8942372 | 0.72 | TOP2A (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL6605949 | 0.68 | LMNA (0.41) | MAP2K1MAP2K2KDM4EALDH1A1HPGD | |
| SCHEMBL9095560 | 0.66 | GAA (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL10341248 | 0.66 | KDM4E (0.50) | MAP2K1MAP2K2KDM4EALDH1A1HPGD | |
| SCHEMBL6050602 | 0.66 | IDO1 (0.51) | MAP2K1MAP2K2KDM4EALDH1A1CAPN1 | |
| SCHEMBL9096358 | 0.65 | MAP2K2 (0.38) | MAP2K1MAP2K2KDM4EALDH1A1GAA | |
| SCHEMBL10341244 | 0.65 | POLB (0.42) | KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442070-A | Derivatives of fluoro-quinoline carboxylic-3-acid and preparation therefor | LABORATOIRE ROGER BELLON (FR) | 1995-08-15 | — | — | US | disclosed |