Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259277 | 0.77 | RAB9A (0.61) | MEN1KMT2AMAOBNPC1RAB9A | |
| SCHEMBL9158037 | 0.77 | KMT2A (0.41) | ALDH1A1MAPTKMT2AHPGDMAOB | |
| SCHEMBL9263722 | 0.77 | NPC1 (0.58) | MEN1KMT2AMAOBNPC1RAB9A | |
| SCHEMBL7662912 | 0.77 | ALDH1A1 (0.64) | ALDH1A1ALDH2MAPTMEN1KMT2A | |
| SCHEMBL9254545 | 0.76 | MAOB (0.61) | ALDH1A1MEN1KMT2AHPGDMAOB | |
| SCHEMBL9159704 | 0.76 | KMT2A (0.41) | MEN1KMT2AMAOBGRM5NPC1 | |
| SCHEMBL9156479 | 0.76 | ALOX5 (0.38) | ALDH1A1MEN1KMT2AHPGDMAOB | |
| SCHEMBL9160911 | 0.76 | MEN1 (0.44) | MEN1KMT2AMAOBGRM5NPC1 | |
| SCHEMBL9161622 | 0.75 | MAOB (0.39) | ALDH1A1HPGDHSD17B10MAOBGRM5 | |
| SCHEMBL9159373 | 0.75 | ALOX5 (0.49) | MEN1KMT2AMAOBGRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424320-A | Antihistamine, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1995-06-13 | — | — | US | claimed |
| US-5360815-A | Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1994-11-01 | — | — | US | disclosed |