SCHEMBL9259300

SCHEMBL9259300

CS(=O)(=O)c1nc2ccc(F)cc2s1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 2/20 0.53
AXL P30530 1/20 0.53
PDPK1 O15530 1/20 0.50
DYRK1A Q13627 1/20 0.50
MAPT P10636 3/20 0.49
LMNA P02545 3/20 0.49
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
PKM P14618 1/20 0.49
ALOX12 P18054 1/20 0.49
MAPK1 P28482 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA4 P22748 2/20 0.47
CCNE1 P24864 1/20 0.47
CDK2 P24941 1/20 0.47
CDK5 Q00535 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9262651 0.87 DYRK1A (0.50) GFERAXLDYRK1ACA1CA2
SCHEMBL32679822 0.84 GFER (0.54) GFERAXLPDPK1DYRK1AMAPT
SCHEMBL10473056 0.83 CA2 (0.69) GFERAXLLMNAKDM4EKMT2A
SCHEMBL14065773 0.81 NPC1 (0.60) DYRK1AMAPTLMNAALDH1A1KDM4E
SCHEMBL11078013 0.80 RAB9A (0.50) DYRK1AMAPTLMNAALDH1A1KDM4E
SCHEMBL11076755 0.80 NPC1 (0.53) DYRK1AMAPTLMNAALDH1A1KDM4E
SCHEMBL9514156 0.80 CA2 (0.47) LMNAALDH1A1KDM4EMEN1KMT2A
SCHEMBL1162535 0.80 CA2 (0.73) MAPTLMNAALDH1A1KDM4EMEN1
SCHEMBL1096269 0.80 CA2 (0.47) MAPTLMNAKDM4EKMT2APKM
SCHEMBL11147940 0.78 CA2 (0.49) LMNAALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104974083-A Dichlorallyl ether compound, insecticide and application of insecticide UNIV HUAZHONG NORMAL 2015-10-14 CN disclosed
US-5442074-A Sulfonyl containing fluorobenzothiazole as chemical intermediate BAYER AKTIENGESELLSCHAFT (DE) 1995-08-15 US disclosed
US-5356864-A New herbicidal fluorobenzothiazolyloxyacetamides BAYER AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
EP-0588183-A1 Fluoro benzothiazolyloxyacetamide BAYER AG (DE) 1994-03-23 EP disclosed