Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 8/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 3/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257483 | 0.90 | TMPRSS15 (0.37) | TMPRSS15MAP4K4CPB1CPB2MIF | |
| SCHEMBL9251133 | 0.88 | TMPRSS15 (0.41) | TMPRSS15ITGB3ITGA2BF10F2 | |
| SCHEMBL9258214 | 0.87 | TMPRSS15 (0.39) | TMPRSS15CPB1CPB2F10F2 | |
| SCHEMBL9257847 | 0.86 | ITGB3 (0.49) | TMPRSS15MAP4K4CPB1CPB2ITGB3 | |
| SCHEMBL9256201 | 0.85 | TMPRSS15 (0.35) | TMPRSS15ITGB3ITGA2BF10F2 | |
| SCHEMBL9252503 | 0.84 | TMPRSS15 (0.35) | TMPRSS15ITGB3ITGA2BF10F2 | |
| SCHEMBL9253069 | 0.84 | MAP4K4 (0.50) | TMPRSS15MAP4K4ITGB3ITGA2BF10 | |
| SCHEMBL8863938 | 0.83 | TMPRSS15 (0.36) | TMPRSS15MAP4K4ITGB3ITGA2BF10 | |
| SCHEMBL9256277 | 0.83 | MAP4K4 (0.36) | TMPRSS15MAP4K4CPB1CPB2MIF | |
| SCHEMBL9251382 | 0.82 | F10 (0.34) | TMPRSS15ITGB3ITGA2BF10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |