Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 9/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 6/20 | 0.34 |
| ▸ | F2 | P00734 | 5/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250993 | 0.88 | ITGB3 (0.38) | TMPRSS15F10F2PRSS1ITGB3 | |
| SCHEMBL9252503 | 0.88 | TMPRSS15 (0.35) | TMPRSS15PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9251382 | 0.86 | F10 (0.34) | TMPRSS15PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9257654 | 0.85 | TMPRSS15 (0.33) | TMPRSS15PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9259335 | 0.85 | TMPRSS15 (0.41) | TMPRSS15F10F2PRSS1ITGB3 | |
| SCHEMBL9251133 | 0.82 | TMPRSS15 (0.41) | TMPRSS15F10F2PRSS1HDAC1 | |
| SCHEMBL9258214 | 0.81 | TMPRSS15 (0.39) | TMPRSS15F10F2PRSS1HDAC1 | |
| SCHEMBL8863938 | 0.78 | TMPRSS15 (0.36) | TMPRSS15PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9568428 | 0.77 | TMPRSS15 (0.34) | TMPRSS15F10F2PRSS1ITGB3 | |
| SCHEMBL9247247 | 0.77 | ITGB3 (0.37) | TMPRSS15PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |