Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130902 | 0.91 | EPHX2 (0.48) | EPHX2ALDH1A1PARP10LMNACASP3 | |
| SCHEMBL8498484 | 0.89 | ALDH1A1 (0.43) | EPHX2ALDH1A1PARP10BTKTSHR | |
| SCHEMBL9225166 | 0.82 | ALDH1A1 (0.49) | EPHX2ALDH1A1PARP10LMNACASP3 | |
| SCHEMBL9259519 | 0.80 | KMT2A (0.48) | EPHX2ALDH1A1PARP10LMNATDP1 | |
| SCHEMBL14114077 | 0.75 | DDB1 (0.41) | ALDH1A1BTKTSHRSMN1; SMN2KMT2A | |
| SCHEMBL19432863 | 0.74 | KMT2A (0.46) | EPHX2ALDH1A1SMN1; SMN2KMT2ASRD5A2 | |
| SCHEMBL14339546 | 0.74 | MAPT (0.49) | ALDH1A1PARP10LMNABTKSMN1; SMN2 | |
| SCHEMBL15131945 | 0.73 | PARP10 (0.58) | EPHX2ALDH1A1PARP10LMNACASP3 | |
| SCHEMBL1028676 | 0.72 | EPHX2 (0.68) | EPHX2ALDH1A1PARP10LMNACASP3 | |
| SCHEMBL4371441 | 0.72 | HRH1 (0.44) | ALDH1A1PARP10BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021815-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND SQUALENE SYNTHASE | ABBOTT LABORATORIES (US) | 1995-08-17 | — | — | WO | disclosed |