Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259518 | 0.80 | EPHX2 (0.41) | KMT2ALMNATDP1FAAHEPHX2 | |
| SCHEMBL3130902 | 0.79 | EPHX2 (0.48) | LMNATDP1FAAHEPHX2PARP10 | |
| SCHEMBL14114077 | 0.78 | DDB1 (0.41) | KMT2AMEN1ALDH1A1NPC1TSHR | |
| SCHEMBL8498484 | 0.78 | ALDH1A1 (0.43) | FAAHEPHX2NAAAPARP10ALDH1A1 | |
| SCHEMBL6539852 | 0.77 | KMT2A (0.59) | KMT2AMEN1LMNASLC6A2SLC6A3 | |
| SCHEMBL19381880 | 0.76 | KMT2A (0.58) | KMT2AMEN1LMNASLC6A2SLC6A3 | |
| SCHEMBL14339546 | 0.74 | MAPT (0.49) | KMT2AMEN1LMNAPARP10ALDH1A1 | |
| SCHEMBL19822418 | 0.73 | LMNA (0.46) | KMT2ALMNASLC6A2SLC6A3KDM4E | |
| SCHEMBL9225166 | 0.72 | ALDH1A1 (0.49) | LMNATDP1FAAHEPHX2PARP10 | |
| SCHEMBL664009 | 0.70 | EPHX2 (0.59) | KMT2AMEN1LMNASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021815-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND SQUALENE SYNTHASE | ABBOTT LABORATORIES (US) | 1995-08-17 | — | — | WO | disclosed |