Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184152 | 0.83 | RAB9A (0.54) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL9263551 | 0.80 | MAPT (0.54) | MAPTLMNASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL9189460 | 0.80 | KMT2A (0.43) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL9185826 | 0.77 | MAPT (0.41) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL9181536 | 0.75 | MAPT (0.40) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL9187035 | 0.75 | HPGD (0.46) | CYP1A2CYP2C9CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL9186890 | 0.73 | DDAH1 (0.45) | ADORA2ACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9183583 | 0.73 | TMEM97 (0.55) | CYP1A2MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7631677 | 0.73 | RAB9A (0.42) | MAPTLMNASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL9184408 | 0.72 | DDAH1 (0.41) | CYP1A2CYP2C9CYP2C19MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451594-A | NEMATOCIDES, INSECTICIDES, MITICIDES AND FUNGICIDES | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| WO-1994006782-A1 | BENZOXAZOLE AND BEZOTHIAZOLE DERIVATIVES | ZENECA LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |