Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 2/20 | 0.46 |
| ▸ | EDNRA | P25101 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257004 | 0.84 | ALDH1A1 (0.76) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL9270554 | 0.80 | ALDH1A1 (0.74) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL1523842 | 0.80 | ALDH1A1 (1.00) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL8358470 | 0.79 | KMT2A (0.72) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL27751714 | 0.78 | PPARD (0.54) | ALDH1A1MAPK14PLA2G2AMAOB | |
| SCHEMBL9270434 | 0.78 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1MAPK14 | |
| SCHEMBL7676057 | 0.77 | LTB4R (0.67) | MAPTALDH1A1KDM4EPLA2G2APOLB | |
| SCHEMBL5471793 | 0.74 | KDM4E (0.61) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL27566887 | 0.73 | ESR1 (0.62) | — | |
| SCHEMBL27438189 | 0.73 | ESR1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| US-5378694-A | Herpes viricide, hypotensive agent | SCHERING CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0550464-A1 | ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS | SCHERING CORPORATION (US) | 1993-07-14 | — | — | EP | disclosed |
| US-5179093-A | Viricides | SCHERING CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| WO-1992004328-A1 | ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |