Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254044 | 0.89 | TBXA2R (0.49) | TBXA2RALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9266948 | 0.89 | TBXA2R (0.49) | TBXA2RALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9254047 | 0.89 | TBXA2R (0.49) | TBXA2RALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9262808 | 0.87 | ALDH1A1 (0.48) | GBA1MAPK1ALDH1A1POLBRAB9A | |
| SCHEMBL8394585 | 0.84 | GBA1 (0.69) | GBA1TBXA2RMAPK1ALDH1A1TDP1 | |
| SCHEMBL9257301 | 0.83 | ALDH1A1 (0.58) | GBA1TBXA2RMAPK1ALDH1A1MEN1 | |
| SCHEMBL9502721 | 0.80 | GBA1 (0.59) | GBA1TBXA2RMAPK1ALDH1A1MEN1 | |
| SCHEMBL9738306 | 0.79 | TBXA2R (0.48) | TBXA2RALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9502716 | 0.78 | GBA1 (0.61) | GBA1TBXA2RMAPK1ALDH1A1TDP1 | |
| SCHEMBL9259702 | 0.78 | ALDH1A1 (0.51) | GBA1TBXA2RMAPK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | claimed |
| EP-0361113-B1 | SULFONAMIDOALKYL CYCLOALKANE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS | Roche Diagnostics GmbH (DE) | 1993-07-07 | — | — | EP | claimed |
| EP-0361113-A1 | Sulfonamidoalkyl cycloalkane compounds, processes for their production and pharmaceutical preparations | Roche Diagnostics GmbH (DE) | 1990-04-04 | — | — | EP | claimed |
| JP-2160761-A | — | — | None | — | — | JP | disclosed |
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | disclosed |
| EP-0361113-B1 | SULFONAMIDOALKYL CYCLOALKANE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS | Roche Diagnostics GmbH (DE) | 1993-07-07 | — | — | EP | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |
| JP-H02160761-A | SULFONAMIDE AND MEDICINE FOR TREATMENT OF CARDIAC-AND CIRCULATORY DISEASE, RENAL DYSFUNCTION, ASTHMA, THROMBOSIS AND BRAIN ISCHEMIC CONDITION CONTAINING IT | BOEHRINGER MANNHEIM GMBH | 1990-06-20 | — | — | JP | disclosed |
| EP-0361113-A1 | Sulfonamidoalkyl cycloalkane compounds, processes for their production and pharmaceutical preparations | Roche Diagnostics GmbH (DE) | 1990-04-04 | — | — | EP | disclosed |