Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394585 | 0.89 | GBA1 (0.69) | ALDH1A1TBXA2RGBA1MAPK1RAB9A | |
| SCHEMBL9502721 | 0.85 | GBA1 (0.59) | ALDH1A1TBXA2RGBA1MAPK1RAB9A | |
| SCHEMBL9502716 | 0.84 | GBA1 (0.61) | ALDH1A1TBXA2RGBA1MAPK1RAB9A | |
| SCHEMBL9259702 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TBXA2RGBA1MAPK1RAB9A | |
| SCHEMBL8391575 | 0.83 | GBA1 (0.60) | ALDH1A1TBXA2RGBA1MAPK1RAB9A | |
| SCHEMBL8393373 | 0.83 | GBA1 (0.60) | ALDH1A1TBXA2RGBA1MAPK1RAB9A | |
| SCHEMBL9259764 | 0.83 | GBA1 (0.50) | ALDH1A1TBXA2RGBA1MAPK1RAB9A | |
| SCHEMBL8397048 | 0.82 | GBA1 (0.58) | ALDH1A1GBA1MAPK1LMNAKDM4E | |
| SCHEMBL8391910 | 0.82 | GBA1 (0.58) | ALDH1A1GBA1MAPK1LMNAKDM4E | |
| SCHEMBL9502641 | 0.81 | GBA1 (0.57) | ALDH1A1TBXA2RGBA1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | disclosed |
| EP-0361113-B1 | SULFONAMIDOALKYL CYCLOALKANE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS | Roche Diagnostics GmbH (DE) | 1993-07-07 | — | — | EP | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |
| EP-0361113-A1 | Sulfonamidoalkyl cycloalkane compounds, processes for their production and pharmaceutical preparations | Roche Diagnostics GmbH (DE) | 1990-04-04 | — | — | EP | disclosed |