Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394585 | 0.94 | GBA1 (0.69) | GBA1MAPK1ALDH1A1PKMLMNA | |
| SCHEMBL8391575 | 0.87 | GBA1 (0.60) | GBA1MAPK1ALDH1A1PKMLMNA | |
| SCHEMBL8393373 | 0.87 | GBA1 (0.60) | GBA1MAPK1ALDH1A1PKMLMNA | |
| SCHEMBL9502721 | 0.86 | GBA1 (0.59) | GBA1MAPK1ALDH1A1PKMLMNA | |
| SCHEMBL8391910 | 0.86 | GBA1 (0.58) | GBA1MAPK1ALDH1A1PKMLMNA | |
| SCHEMBL8397048 | 0.86 | GBA1 (0.58) | GBA1MAPK1ALDH1A1PKMLMNA | |
| SCHEMBL9502641 | 0.84 | GBA1 (0.57) | GBA1MAPK1ALDH1A1PKMLMNA | |
| SCHEMBL8395503 | 0.84 | ALDH1A1 (0.66) | GBA1MAPK1ALDH1A1PKMLMNA | |
| SCHEMBL9257301 | 0.84 | ALDH1A1 (0.58) | GBA1MAPK1ALDH1A1PKMLMNA | |
| SCHEMBL17205770 | 0.83 | GBA1 (0.55) | GBA1MAPK1ALDH1A1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361113-B1 | SULFONAMIDOALKYL CYCLOALKANE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS | Roche Diagnostics GmbH (DE) | 1993-07-07 | — | — | EP | claimed |