Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17984632 | 0.83 | GAA (0.48) | ROCK2ROCK1GAATDP1SIRT3 | |
| Hydrochloric Acid SCHEMBL23850379 | 0.82 | GAA (0.47) | ROCK2ROCK1GAATDP1SIRT3 | |
| SCHEMBL25595777 | 0.79 | ROCK2 (0.47) | ROCK2ROCK1GAATDP1SIRT3 | |
| SCHEMBL651312 | 0.79 | SIRT3 (0.60) | ROCK2ROCK1GAATDP1SIRT3 | |
| SCHEMBL5342341 | 0.79 | CYP2A6 (0.47) | ROCK2ROCK1GAATDP1SIRT3 | |
| SCHEMBL7958530 | 0.77 | GAA (0.45) | GAATDP1SIRT3MEN1KMT2A | |
| SCHEMBL1421583 | 0.77 | SIRT3 (0.42) | TDP1SIRT3MKNK1MKNK2HPGD | |
| Hydrochloric Acid SCHEMBL7949698 | 0.75 | GAA (0.43) | GAATDP1SIRT3MEN1KMT2A | |
| SCHEMBL587010 | 0.72 | ROCK2 (0.58) | ROCK2ROCK1GAATDP1SIRT3 | |
| SCHEMBL15514423 | 0.72 | ROCK2 (0.58) | ROCK2ROCK1GAATDP1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393752-A | Psycholigical disorders | THERABEL RESEARCH S.A./N.V. (BE) | 1995-02-28 | — | — | US | disclosed |