Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826357 | 0.83 | MKNK1 (0.58) | SIRT3TDP1ROCK2ROCK1MKNK1 | |
| Hydrochloric Acid SCHEMBL28637331 | 0.82 | MKNK1 (0.57) | SIRT3TDP1ROCK2ROCK1MKNK1 | |
| SCHEMBL29574646 | 0.81 | ROCK2 (0.58) | SIRT3TDP1ROCK2ROCK1KDM4E | |
| SCHEMBL7533 | 0.81 | ROCK2 (0.58) | SIRT3TDP1ROCK2ROCK1KDM4E | |
| SCHEMBL30465597 | 0.81 | ROCK2 (0.58) | SIRT3TDP1ROCK2ROCK1MKNK1 | |
| SCHEMBL15514423 | 0.81 | ROCK2 (0.58) | SIRT3TDP1ROCK2ROCK1MKNK1 | |
| SCHEMBL587010 | 0.81 | ROCK2 (0.58) | SIRT3TDP1ROCK2ROCK1MKNK1 | |
| SCHEMBL1687197 | 0.80 | TDP1 (0.67) | SIRT3TDP1ROCK1MKNK1MKNK2 | |
| SCHEMBL1330970 | 0.80 | TDP1 (0.67) | SIRT3TDP1ROCK1MKNK1MKNK2 | |
| SCHEMBL9437660 | 0.80 | SIRT3 (0.50) | SIRT3TDP1MKNK1MKNK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573559-B | Nicotinamide tetrazole lead complex, synthesis method and application | 西安近代化学研究所 | 2023-05-12 | — | — | CN | claimed |
| CN-115747298-A | Insect nicotinamide enzyme inhibitor and identification method and application of insect nicotinamide enzyme inhibitor to pesticide | 浙江大学 | 2023-03-07 | — | — | CN | claimed |
| CN-109688816-A | Active compound combinations and method for protecting plant propagation material | 拜耳作物科学股份公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109485602-A | A kind of chloro- N- of 2- (phenylcarbamoyl) nicotinamide compound and its preparation method and application | 浙江工业大学 | 2019-03-19 | — | — | CN | claimed |
| US-6028111-A | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents | OXIGENE, INC. (US) | 2000-02-22 | — | — | US | claimed |
| EP-0315151-A2 | Process for the preparation of imidized acrylic polymers | ELF ATOCHEM ITALIA S.r.l. (IT) | 1989-05-10 | — | — | EP | claimed |
| EP-4613857-A1 | AMIDASE MUTANT AND USE THEREOF | Asymchem Life Science (Tianjin) Co., Ltd (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-116267965-B | Application of curcumenol derivative in preparing medicament for preventing and treating plant pathogenic fungi | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2025-06-03 | — | — | CN | disclosed |
| CN-119798151-A | 5-Substituted amino-5 '-acetamido-3, 3' -bipyridine derivative and preparation method and application thereof | 南京合谷生命生物科技有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-116083406-B | Amidase mutant and application thereof | 凯莱英生命科学技术(天津)有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119638737-A | Macrocyclic compounds and their use in medicine | 广东东阳光药业股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-118561939-B | Nicotinamide ribose malate crystal form and preparation method and application thereof | 邦泰生物工程(深圳)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-117285437-B | Bexarotene derivative, preparation method and application thereof, and anti-tumor drug | 沈阳药科大学 | 2024-09-17 | — | — | CN | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4080336-A | Process for the production of 2-chloronicotinic acid amide | LONZA LTD. (CH) | 1978-03-21 | — | — | US | disclosed |