Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265072 | 0.87 | NPSR1 (0.49) | KDRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9260790 | 0.76 | MEN1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL995474 | 0.70 | KDR (1.00) | KDRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2077491 | 0.70 | TMPRSS4 (0.74) | KDRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9260067 | 0.70 | ALDH1A1 (0.47) | NPC1SMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9259716 | 0.70 | LCK (0.45) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27866684 | 0.70 | NPC1 (0.80) | KDRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5578096 | 0.69 | NPC1 (0.81) | KDRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL651159 | 0.68 | KDR (0.74) | KDRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL935558 | 0.68 | NPC1 (0.70) | KDRNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |