Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 11/20 | 0.47 |
| ▸ | RAB9A | P51151 | 11/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259716 | 0.76 | LCK (0.45) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9259818 | 0.76 | KDR (0.53) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL7817781 | 0.71 | CA12 (0.37) | MEN1KMT2AALDH1A1POLBHPGD | |
| SCHEMBL27792368 | 0.71 | KCNMA1 (0.74) | MEN1KMT2AKDM4EALDH1A1GLA | |
| SCHEMBL2269809 | 0.71 | NPC1 (0.69) | MEN1KMT2AKDM4EALDH1A1GLA | |
| SCHEMBL9255027 | 0.70 | CA12 (0.45) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL5011704 | 0.70 | RAB9A (0.86) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL9260067 | 0.69 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL11729468 | 0.69 | NPC1 (0.58) | MEN1KMT2AKDM4EALDH1A1GLA | |
| SCHEMBL9257855 | 0.68 | KDM4E (0.50) | MEN1KMT2AKDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |