Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264816 | 0.83 | CA12 (0.53) | CA9CA12LMNAMEN1KMT2A | |
| SCHEMBL9257755 | 0.80 | ADORA3 (0.54) | CA9CA12ALDH1A1CYP1A2GAA | |
| SCHEMBL14773373 | 0.78 | CA12 (0.38) | CA9CA12LMNAALDH1A1KMT2A | |
| SCHEMBL9259884 | 0.78 | LMNA (0.44) | LMNAALDH1A1HPGDCHEK1PTGS2 | |
| SCHEMBL9259425 | 0.78 | DDR1 (0.39) | CA9CA12ALDH1A1CYP1A2GAA | |
| SCHEMBL13825521 | 0.77 | CA12 (0.41) | CA9CA12ALDH1A1GAAHPGD | |
| SCHEMBL9259395 | 0.76 | CA12 (0.41) | CA9CA12CA1CA2CMA1 | |
| SCHEMBL9252371 | 0.75 | FEN1 (0.44) | CMA1PTGS2 | |
| SCHEMBL9257826 | 0.75 | FEN1 (0.55) | CA9CA12MEN1KMT2ACA1 | |
| SCHEMBL9264560 | 0.75 | CA12 (0.55) | CA9CA12MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | claimed |
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |