Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259395 | 0.84 | CA12 (0.41) | FEN1CMA1 | |
| SCHEMBL9257826 | 0.83 | FEN1 (0.55) | FEN1 | |
| SCHEMBL9255973 | 0.82 | PARP1 (0.47) | PTGS2 | |
| SCHEMBL9258552 | 0.81 | KDM4E (0.47) | — | |
| SCHEMBL9259975 | 0.81 | CA9 (0.43) | FEN1CMA1 | |
| SCHEMBL9262316 | 0.81 | KIF11 (0.42) | FEN1CMA1 | |
| SCHEMBL9257797 | 0.80 | CA12 (0.58) | — | |
| SCHEMBL9264418 | 0.80 | FEN1 (0.58) | FEN1PTGS2 | |
| SCHEMBL9261018 | 0.80 | ALK (0.39) | — | |
| SCHEMBL9255519 | 0.80 | CCNB2 (0.36) | FEN1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | claimed |
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |