Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600481 | 0.81 | PIM1 (0.71) | PIM1PIM2ADAM17CYP26B1CYP26A1 | |
| SCHEMBL9263927 | 0.81 | LMNA (0.63) | PIM1PIM2ADAM17CYP26B1CYP26A1 | |
| Methylene Chloride SCHEMBL28171003 | 0.81 | PIM1 (0.66) | PIM1PIM2ADAM17CYP26B1CYP26A1 | |
| SCHEMBL16708233 | 0.80 | TAS1R3 (0.53) | PIM1ADAM17LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3721823 | 0.78 | PIM1 (0.68) | PIM1ADAM17LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2096338 | 0.77 | NPC1 (0.54) | PIM1ADAM17SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18313582 | 0.77 | ALDH1A1 (0.47) | PIM1PIM2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL9260289 | 0.77 | LMNA (0.42) | PIM1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL8310947 | 0.77 | TAS1R3 (0.59) | HPGDKDM4EALDH1A1FLT3HDAC6 | |
| SCHEMBL9263275 | 0.76 | NPC1 (0.48) | PIM1PIM2ADAM17CYP26B1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | claimed |
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0601181-A1 | BENZOFURAN DERIVATIVE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1994-06-15 | — | — | EP | disclosed |