Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CPA3 | P15088 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258279 | 0.86 | FAAH (0.41) | FAAHEPHX2 | |
| SCHEMBL9254477 | 0.82 | CYP1A2 (0.43) | CYP1A2FOLH1CPA3MEN1KMT2A | |
| SCHEMBL7491183 | 0.82 | CYP1A2 (0.47) | CYP1A2FOLH1CPA3CPA1 | |
| SCHEMBL7490323 | 0.81 | CYP1A2 (0.46) | CYP1A2FOLH1CPA3CPA1 | |
| SCHEMBL9258103 | 0.80 | MAPK1 (0.46) | CYP1A2FOLH1CPA3KMT2ACPA1 | |
| SCHEMBL9259942 | 0.79 | MAPT (0.39) | CYP1A2TLR2MEN1KMT2A | |
| SCHEMBL9257787 | 0.78 | CYP1A2 (0.43) | CYP1A2FOLH1CPA3CPA1 | |
| SCHEMBL16144031 | 0.78 | MEN1 (0.52) | PTGESALOX5PPARGCYP1A2FOLH1 | |
| SCHEMBL9259001 | 0.77 | CYP1A2 (0.47) | CYP1A2FOLH1CPA3CPA1 | |
| SCHEMBL9259162 | 0.77 | ACE2 (0.43) | CYP1A2FOLH1CPA3CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |