Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260024 | 0.86 | TBXAS1 (0.49) | ALOX5TBXAS1 | |
| SCHEMBL9260118 | 0.85 | ALOX5 (0.56) | ALOX5EPHX2 | |
| SCHEMBL9257237 | 0.85 | ALOX5 (0.42) | ALOX5EPHX2 | |
| SCHEMBL9260680 | 0.85 | ALOX5 (0.56) | ALOX5EPHX2 | |
| SCHEMBL9258162 | 0.83 | ALOX5 (0.46) | ALOX5EPHX2 | |
| SCHEMBL9287219 | 0.80 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9264598 | 0.80 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL9288892 | 0.80 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9267255 | 0.79 | SLC1A3 (0.39) | ALOX5 | |
| SCHEMBL9287450 | 0.77 | ALOX5 (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030671-A1 | SUBSTITUTED ARYL- AND HETEROARYLALKENYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1995-11-16 | — | — | WO | claimed |
| WO-1995030671-A1 | SUBSTITUTED ARYL- AND HETEROARYLALKENYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1995-11-16 | — | — | WO | disclosed |