Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258162 | 0.84 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9260680 | 0.81 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9260118 | 0.81 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9257237 | 0.81 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9259905 | 0.80 | ALOX5 (0.36) | ALOX5 | |
| SCHEMBL9260002 | 0.79 | ALOX5 (0.40) | ALOX5 | |
| SCHEMBL9025861 | 0.77 | ALOX5 (0.49) | SLC1A3SLC1A2SLC1A1ALOX5TBXA2R | |
| SCHEMBL9260024 | 0.77 | TBXAS1 (0.49) | ALOX5 | |
| SCHEMBL9287219 | 0.76 | ALOX5 (0.45) | SLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL9264598 | 0.76 | ALOX5 (0.38) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030671-A1 | SUBSTITUTED ARYL- AND HETEROARYLALKENYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1995-11-16 | — | — | WO | disclosed |