Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261003 | 0.77 | PRMT6 (0.42) | ERN1CYP2A6PRMT6HDAC1HDAC6 | |
| SCHEMBL27605043 | 0.68 | ACMSD (0.45) | ERN1CHEK2MAPTCYP2A6HDAC6 | |
| SCHEMBL9260467 | 0.68 | PELI1 (0.32) | ERN1CYP2A6EEF2KDYRK3JAK2 | |
| SCHEMBL9260479 | 0.68 | PELI1 (0.32) | ERN1CYP2A6EEF2KDYRK3JAK2 | |
| SCHEMBL23330723 | 0.67 | KDM4E (0.40) | ERN1CHEK2MEN1USP2MAPT | |
| SCHEMBL23330930 | 0.66 | ADORA1 (0.40) | ERN1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL9454086 | 0.65 | CYP2A6 (0.42) | ERN1CYP2A6PRMT6EEF2KDYRK3 | |
| SCHEMBL23331113 | 0.64 | ACMSD (0.42) | ERN1CHEK2CYP2A6HDAC1HDAC6 | |
| SCHEMBL24721657 | 0.64 | ERN1 (0.39) | ERN1CHEK2MEN1KMT2ACYP2A6 | |
| SCHEMBL23300793 | 0.63 | ACMSD (0.41) | MEN1KMT2ACYP2A6HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |