Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.31 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.31 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260467 | 1.00 | PELI1 (0.32) | PELI1ERN1CYP2A6EEF2KDYRK3 | |
| SCHEMBL9261007 | 0.79 | PRMT6 (0.38) | PELI1ERN1CYP2A6EEF2KDYRK3 | |
| SCHEMBL9260999 | 0.79 | PRMT6 (0.38) | PELI1ERN1CYP2A6EEF2KDYRK3 | |
| SCHEMBL9256414 | 0.75 | CYP2A6 (0.38) | PELI1ERN1CYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9256407 | 0.75 | CYP2A6 (0.38) | PELI1ERN1CYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9258123 | 0.70 | SQLE (0.55) | — | |
| SCHEMBL9258130 | 0.70 | SQLE (0.55) | — | |
| SCHEMBL9254956 | 0.68 | HCAR2 (0.49) | ERN1CYP2A6CYP2E1CYP2B6KCNH2 | |
| SCHEMBL9254963 | 0.68 | HCAR2 (0.49) | ERN1CYP2A6CYP2E1CYP2B6KCNH2 | |
| SCHEMBL9260475 | 0.68 | ERN1 (0.33) | ERN1CYP2A6EEF2KDYRK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |