Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | CCR2 | P41597 | 4/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | PLA2G10 | O15496 | 8/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428197 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TSHRCCR2DAOPLA2G10 | |
| SCHEMBL30194196 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TSHRCCR2DAOPLA2G10 | |
| SCHEMBL5208338 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TSHRCCR2DAOPLA2G10 | |
| SCHEMBL9149430 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TSHRCCR2DAOPLA2G10 | |
| SCHEMBL5421995 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TSHRCCR2DAOPLA2G10 | |
| SCHEMBL9260948 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TSHRCCR2DAOPLA2G10 | |
| SCHEMBL3957422 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TSHRCCR2DAOPLA2G10 | |
| SCHEMBL5434782 | 0.79 | ALDH1A1 (0.77) | ALDH1A1TSHRCCR2DAOPLA2G10 | |
| SCHEMBL5247396 | 0.79 | ALDH1A1 (0.76) | ALDH1A1TSHRCCR2DAOPLA2G10 | |
| Dimethylamine SCHEMBL4930574 | 0.79 | ALDH1A1 (0.87) | ALDH1A1TSHRCCR2DAOPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466704-A | N-substituted imidazole and benzimidazole derivatives useful as angiotenson II antagonists | E. R. SQUIBB & SONS, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| EP-0501269-A1 | Imidazole and benzimidazole derivatives | E.R. SQUIBB & SONS, INC. (US) | 1992-09-02 | — | — | EP | disclosed |