Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981154 | 0.88 | KMT2A (0.43) | KMT2AMEN1MAPTHTTHPGD | |
| SCHEMBL9260591 | 0.84 | MEN1 (0.34) | KMT2AMEN1MAPTHTTNAMPT | |
| SCHEMBL6978226 | 0.84 | MEN1 (0.34) | KMT2AMEN1MAPTHTTNAMPT | |
| SCHEMBL9260617 | 0.82 | ITGB3 (0.45) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9261117 | 0.82 | ITGB3 (0.45) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7323432 | 0.73 | LPAR2 (0.62) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL31048772 | 0.70 | PPIA (0.42) | KDM4EKMT2AMEN1MAPTHTT | |
| SCHEMBL6980785 | 0.70 | CA12 (0.59) | KDM4EKMT2AMEN1MAPTHTT | |
| SCHEMBL6979118 | 0.69 | ALDH1A1 (0.33) | KMT2AMEN1MAPTNAMPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6983894 | 0.69 | CA12 (0.57) | KDM4EKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |