Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 7/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978226 | 1.00 | MEN1 (0.34) | MEN1KMT2AL3MBTL1NAMPTCYP3A4 | |
| SCHEMBL6979118 | 0.85 | ALDH1A1 (0.33) | MEN1KMT2AL3MBTL1NAMPTSMN1; SMN2 | |
| SCHEMBL6981154 | 0.85 | KMT2A (0.43) | MEN1KMT2AL3MBTL1HTTMAPT | |
| SCHEMBL9260637 | 0.84 | KDM4E (0.38) | MEN1KMT2ANAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9260554 | 0.82 | ITGB3 (0.42) | PARP1PARP10 | |
| SCHEMBL9257934 | 0.82 | ITGB3 (0.42) | PARP1PARP10 | |
| SCHEMBL9425678 | 0.78 | ITGB3 (0.42) | — | |
| SCHEMBL6972945 | 0.76 | PARP1 (0.49) | MEN1KMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9425694 | 0.76 | TRPM8 (0.38) | MEN1KMT2AL3MBTL1NAMPTCYP3A4 | |
| Hydrochloric Acid SCHEMBL7351854 | 0.75 | PARP1 (0.48) | MEN1KMT2AL3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |