Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.48 |
| ▸ | UBE2M | P61081 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256017 | 0.90 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2DCUN1D1UBE2MTP53 | |
| SCHEMBL9261691 | 0.89 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2ROCK2DCUN1D1UBE2M | |
| SCHEMBL9255834 | 0.89 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2ROCK2DCUN1D1UBE2M | |
| SCHEMBL9257544 | 0.89 | SLC6A9 (0.59) | ALDH1A1SMN1; SMN2ROCK2DCUN1D1UBE2M | |
| SCHEMBL9257297 | 0.89 | DCUN1D1 (0.56) | ALDH1A1SMN1; SMN2ROCK2DCUN1D1UBE2M | |
| SCHEMBL9265728 | 0.89 | AGER (0.56) | ALDH1A1SMN1; SMN2ROCK2DCUN1D1UBE2M | |
| SCHEMBL9255607 | 0.89 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2ROCK2DCUN1D1UBE2M | |
| Hydrochloric Acid SCHEMBL9262873 | 0.88 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2ROCK2DCUN1D1UBE2M | |
| SCHEMBL9263610 | 0.87 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2ROCK2DCUN1D1UBE2M | |
| SCHEMBL9260631 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2ROCK2DCUN1D1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384425-A | Diurea derivatives useful as medicaments and processes for the preparation thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-01-24 | — | — | US | disclosed |
| EP-0325397-B1 | DIUREA DERIVATIVES USEFUL AS MEDICAMENTS AND PROCESSES FOR THE PREPARATION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5227492-A | Anticholesterol agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5166429-A | Enzyme inhibitors of acylcoenzyme A cholesterol transferase as anticholesterol agents or antideposit agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| US-5091419-A | Anticholesterol agent | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |