Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272694 | 0.86 | VHL (0.40) | BIRC5APPCYP19A1SCN9ACA1 | |
| SCHEMBL9264222 | 0.76 | XDH (0.46) | — | |
| SCHEMBL15374934 | 0.74 | SCN9A (0.53) | CYP19A1SCN9A | |
| SCHEMBL5485099 | 0.70 | BIRC5 (0.66) | BIRC5CYP19A1 | |
| SCHEMBL30175561 | 0.67 | RAB9A (0.43) | — | |
| SCHEMBL30175560 | 0.67 | MAP3K8 (0.41) | — | |
| SCHEMBL17069069 | 0.66 | XDH (0.39) | CA1CA2 | |
| SCHEMBL7848653 | 0.66 | CA1 (0.39) | APPCYP19A1CA1CA2 | |
| SCHEMBL2872955 | 0.65 | KMT2A (0.51) | APPCA1CA2SNCA | |
| SCHEMBL21725642 | 0.63 | HTR2A (0.36) | CYP19A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466704-A | N-substituted imidazole and benzimidazole derivatives useful as angiotenson II antagonists | E. R. SQUIBB & SONS, INC. (US) | 1995-11-14 | — | — | US | disclosed |