Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296099 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| SCHEMBL27880534 | 0.82 | PDCD1 (0.50) | ALDH1A1MAPTNPC1RAB9AHTT | |
| SCHEMBL3963549 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| SCHEMBL6927417 | 0.80 | FGFR1 (0.58) | ALDH1A1KMT2AATMKDM4EFGFR1 | |
| Biphenyl SCHEMBL23023808 | 0.78 | ALDH1A1 (0.86) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| SCHEMBL27349113 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| SCHEMBL2222831 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTTDP1KMT2A | |
| SCHEMBL42787 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| SCHEMBL29387332 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| SCHEMBL8144263 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446057-A | Antiulcer agent, antisecretory agent, drug treating urogenital disorder, parkinson*s disease and alzheimer*s disease | WARNER-LAMBERT COMPANY (US) | 1995-08-29 | — | — | US | disclosed |