Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9261091 | 0.98 | PDE4D (0.37) | PDE4DRIPK1DRD2DRD1DRD3 | |
| SCHEMBL29446629 | 0.82 | RAB9A (0.41) | PDE4DPDE4BTDP1PDE4AKCNH2 | |
| SCHEMBL2690888 | 0.82 | RAB9A (0.41) | PDE4DPDE4BTDP1PDE4AKCNH2 | |
| Hydrochloric Acid SCHEMBL28857260 | 0.80 | RAB9A (0.43) | PDE4DPDE4BTDP1PDE4AKCNH2 | |
| Hydrochloric Acid SCHEMBL29362717 | 0.80 | RAB9A (0.43) | PDE4DPDE4BTDP1PDE4AKCNH2 | |
| Hydrochloric Acid SCHEMBL1002426 | 0.80 | RAB9A (0.43) | PDE4DPDE4BTDP1PDE4AKCNH2 | |
| SCHEMBL27309511 | 0.75 | ALOX5AP (0.35) | — | |
| Hydrochloric Acid SCHEMBL3169911 | 0.75 | RAB9A (0.37) | TDP1 | |
| Hydrochloric Acid SCHEMBL10583439 | 0.75 | ATP4A (0.42) | PDE4BTDP1 | |
| Hydrochloric Acid SCHEMBL27309513 | 0.74 | ALOX5AP (0.35) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430042-A | Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use | AKTIEBOLAGET ASTRA (SE) | 1995-07-04 | — | — | US | disclosed |