Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719197 | 0.83 | HTR3E (0.41) | MAPTMAPK1HCAR3GAAGLA | |
| SCHEMBL4138824 | 0.80 | MAPK1 (0.75) | MAPTMAPK1GAAHTTMEN1 | |
| SCHEMBL4726250 | 0.80 | MAPT (0.43) | MAPTMAPK1HCAR3GAACYP1A2 | |
| SCHEMBL4014589 | 0.79 | HCAR3 (0.41) | MAPTMAPK1HCAR3GAAGLA | |
| SCHEMBL4015597 | 0.79 | HCAR3 (0.41) | MAPTMAPK1HCAR3GAAGLA | |
| SCHEMBL27680575 | 0.79 | HCAR3 (0.40) | MAPTMAPK1HCAR3GAACYP1A2 | |
| SCHEMBL3605970 | 0.78 | ALDH1A1 (0.50) | MAPTMAPK1HTTALDH1A1L3MBTL1 | |
| SCHEMBL718625 | 0.76 | MAPK1 (0.65) | MAPTMAPK1HCAR3GAAGLA | |
| SCHEMBL9260905 | 0.76 | ALDH1A1 (0.45) | MAPK1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3057719 | 0.74 | LMNA (0.50) | MAPTMAPK1HCAR3GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555780-A | Syk inhibitors | GILEAD SCIENCES INC | 2016-05-04 | — | — | CN | disclosed |