Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731212 | 1.00 | CHRM5 (0.48) | CHRM5ADRA2CACHEGBA1RAD52 | |
| SCHEMBL2912326 | 1.00 | CHRM5 (0.48) | CHRM5ADRA2CACHEGBA1RAD52 | |
| SCHEMBL20873850 | 1.00 | CHRM5 (0.48) | CHRM5ADRA2CACHEGBA1RAD52 | |
| Bromide SCHEMBL31114948 | 0.97 | CHRM5 (0.46) | CHRM5ADRA2CACHEGBA1RAD52 | |
| Hydrochloric Acid SCHEMBL21001940 | 0.97 | CHRM5 (0.46) | CHRM5ADRA2CACHEGBA1RAD52 | |
| Hydrochloric Acid SCHEMBL4668199 | 0.97 | CHRM5 (0.46) | CHRM5ADRA2CACHEGBA1RAD52 | |
| Hydrochloric Acid SCHEMBL5570644 | 0.97 | CHRM5 (0.46) | CHRM5ADRA2CACHEGBA1RAD52 | |
| SCHEMBL2570307 | 0.92 | GBA1 (0.47) | CHRM5ADRA2CACHEGBA1RAD52 | |
| SCHEMBL1268833 | 0.91 | ADRA2C (0.52) | CHRM5ADRA2CACHEGBA1RAD52 | |
| SCHEMBL211956 | 0.90 | CHRM5 (0.56) | CHRM5ADRA2CACHEGBA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 836 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119391811-A | Application of piperazine derivative in bacteriostasis of spoilage bacteria | 黄河科技学院 | 2025-02-07 | — | — | CN | claimed |
| CN-118684644-A | Eupatilin derivative containing piperazine structure and preparation method and application thereof | 南阳医学高等专科学校 | 2024-09-24 | — | — | CN | claimed |
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | NOVARTIS AG (CH) | 2023-10-17 | — | — | US | claimed |
| US-20230108325-A1 | Pyrazolopyridine Derivatives and Uses thereof | NOVARTIS AG (CH) | 2023-04-06 | — | — | US | claimed |
| CN-108341792-B | Preparation method of Volasertib intermediate 1-cyclopropyl methyl piperazine | 苏州莱克施德药业有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-113200908-A | Tertiary amine-containing anthranilamide compound and preparation and application thereof | 南华大学 | 2021-08-03 | — | — | CN | claimed |
| CN-106660955-A | Cyclohexene derivative, preparation method therefor, and pharmaceutical composition for preventing or treating metabolic diseases, containing same as active ingredient | 现代药品株式会社 | 2017-05-10 | — | — | CN | claimed |
| EP-3044210-A2 | NOVEL CYTOCHROME P450 INHIBITORS AND THEIR METHOD OF USE | Cortendo AB (publ) (US) | 2016-07-20 | — | — | EP | claimed |
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | claimed |
| CN-104046246-A | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PROD & CHEM | 2014-09-17 | — | — | CN | claimed |
| EP-1778668-B1 | METHOD FOR THE PRODUCTION OF DIHYDROPTERIDINONES | BOEHRINGER INGELHEIM INT (DE) | 2013-07-03 | — | — | EP | claimed |
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | claimed |
| US-20090054411-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | US | claimed |
| EP-2010496-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | AstraZeneca AB (SE) | 2009-01-07 | — | — | EP | claimed |
| WO-2007119046-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | WO | claimed |
| US-6355635-B1 | IMIDAZOLEBENZENE, IMIDAZOLEPYRIDINE COMPOUNDS FOR TREATMENT OF OBESITY | PFIZER INC. | 2002-03-12 | — | — | US | claimed |
| US-20010039277-A1 | Compounds for the treatment of obesity | ELLIOTT RICHARD L (US) | 2001-11-08 | — | — | US | claimed |
| WO-2000066578-A1 | COMPOUNDS FOR THE TREATMENT OF OBESITY | PFIZER PRODUCTS INC. (US) | 2000-11-09 | — | — | WO | claimed |
| EP-0050072-B1 | CYCLOPROPYL METHYL PIPERAZINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPEUTICS | INNOTHERA (FR) | 1984-12-27 | — | — | EP | claimed |
| EP-0050072-A1 | Cyclopropyl methyl piperazines, process for their preparation and their use in therapeutics | INNOTHERA (FR) | 1982-04-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | HBZ, ZFX, WIZ | CHRM5 4105/4885ADRA2C 2057/4885ACHE 4474/4885 |
| US-20010039277-A1 | Compounds for the treatment of obesity | NPY1R, NPY4R, NPY2R | CHRM5 731/4885ADRA2C 181/4885ACHE 2598/4885 |
| US-20230108325-A1 | Pyrazolopyridine Derivatives and Uses thereof | HBZ, ZFX, WIZ | CHRM5 4105/4885ADRA2C 2057/4885ACHE 4474/4885 |
| US-20090054411-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | CSF1R, CSF3R, FLT3 | CHRM5 2693/4885ADRA2C 2470/4885ACHE 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.