Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251017 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTADRB2TRPM8NPC1 | |
| SCHEMBL9262605 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTADRB2TRPM8NPC1 | |
| SCHEMBL9255559 | 0.82 | MAPT (0.40) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9262570 | 0.78 | NR1H2 (0.37) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9261032 | 0.75 | MAPT (0.48) | ALDH1A1MAPTADRB2TRPM8NPC1 | |
| SCHEMBL9259471 | 0.74 | ALOX15 (0.41) | ALDH1A1MAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9261637 | 0.74 | ALOX15 (0.41) | ALDH1A1MAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9258671 | 0.71 | SMN1; SMN2 (0.38) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9262112 | 0.70 | MAPT (0.43) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9255807 | 0.70 | MAPT (0.41) | ALDH1A1MAPTADRB2TRPM8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |