Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HTR1D | P28221 | 2/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557448 | 0.89 | GPR84 (0.62) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL10981163 | 0.89 | GPR84 (0.62) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL4349467 | 0.88 | NPC1 (0.68) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL8559329 | 0.87 | GPR84 (0.64) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL9096170 | 0.87 | GPR84 (0.64) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL3974212 | 0.85 | NPC1 (0.80) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL12844152 | 0.85 | GPR84 (0.68) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL27427278 | 0.84 | GPR84 (0.67) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL2534004 | 0.84 | HTR1A (0.73) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL8806861 | 0.84 | GPR84 (0.67) | GPR84NPC1HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418237-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-05-23 | — | — | US | disclosed |