Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263259 | 1.00 | SLC6A3 (0.44) | SLC6A3CHRNB2CHRNA4CHRNA3CHRNA7 | |
| SCHEMBL9462280 | 0.84 | SLC6A3 (0.41) | SLC6A3CHRNB2CHRNA4CHRNA3CHRNA7 | |
| SCHEMBL9256443 | 0.84 | SLC6A3 (0.41) | SLC6A3CHRNB2CHRNA4CHRNA3CHRNA7 | |
| SCHEMBL9265344 | 0.76 | CHRNB2 (0.34) | CHRNB2CHRNA4CHRNA3CHRNA7 | |
| SCHEMBL9265349 | 0.76 | CHRNB2 (0.34) | CHRNB2CHRNA4CHRNA3CHRNA7 | |
| SCHEMBL9462242 | 0.70 | SLC6A4 (0.53) | SLC6A3 | |
| SCHEMBL9462238 | 0.70 | SLC6A4 (0.53) | SLC6A3 | |
| SCHEMBL9261192 | 0.66 | CHRM2 (0.63) | SLC6A3 | |
| SCHEMBL7690579 | 0.64 | MEN1 (0.47) | — | |
| SCHEMBL7687685 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391744-A | Enhanced analgesic and vasoconstrictive properties | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1995-02-21 | — | — | US | disclosed |
| US-5268480-A | Containing an aromatic ester | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1993-12-07 | — | — | US | disclosed |