Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265344 | 1.00 | CHRNB2 (0.34) | CHRNB2CHRNA3CHRNA7CHRNA4CHRM2 | |
| SCHEMBL9462280 | 0.78 | SLC6A3 (0.41) | CHRNB2CHRNA3CHRNA7CHRNA4CHRM2 | |
| SCHEMBL9256443 | 0.78 | SLC6A3 (0.41) | CHRNB2CHRNA3CHRNA7CHRNA4CHRM2 | |
| SCHEMBL9263259 | 0.76 | SLC6A3 (0.44) | CHRNB2CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL9263264 | 0.76 | SLC6A3 (0.44) | CHRNB2CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL9462238 | 0.75 | SLC6A4 (0.53) | — | |
| SCHEMBL9462242 | 0.75 | SLC6A4 (0.53) | — | |
| SCHEMBL851669 | 0.69 | PPM1D (0.30) | — | |
| SCHEMBL29367912 | 0.69 | TDP1 (0.50) | LMNACYP2C9 | |
| SCHEMBL5397645 | 0.69 | SLC6A3 (0.40) | LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391744-A | Enhanced analgesic and vasoconstrictive properties | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1995-02-21 | — | — | US | disclosed |
| US-5268480-A | Containing an aromatic ester | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1993-12-07 | — | — | US | disclosed |