Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258376 | 0.90 | ALOX5 (0.45) | ALOX5MAOBARKDM4ESMN1; SMN2 | |
| SCHEMBL9264414 | 0.90 | ALOX5 (0.57) | ALOX5MAOBKDM4ESMN1; SMN2TUBB | |
| SCHEMBL9269565 | 0.85 | MAOB (0.49) | ALOX5MAOBARSMN1; SMN2 | |
| SCHEMBL9259265 | 0.81 | ALOX5 (0.37) | ALOX5MAOBARKDM4EBCHE | |
| SCHEMBL9258559 | 0.76 | MAOB (0.48) | MAOBARMAOA | |
| SCHEMBL9261473 | 0.75 | MAOB (0.41) | MAOBKDM4ESMN1; SMN2 | |
| SCHEMBL9265290 | 0.75 | MAOB (0.63) | MAOBARKDM4ESMN1; SMN2MAOA | |
| SCHEMBL9263552 | 0.75 | MAOB (0.47) | MAOBARMAOA | |
| SCHEMBL9268130 | 0.74 | MAOB (0.46) | MAOBARMAOA | |
| SCHEMBL9261102 | 0.72 | MAOB (0.49) | ALOX5MAOBARSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424320-A | Antihistamine, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1995-06-13 | — | — | US | disclosed |
| US-5360815-A | Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1994-11-01 | — | — | US | disclosed |